Introduction

psiNAT MDR TB Real Time PCR Test kit for the qualitative/quantitative detection of nucleic acidSputum, BAL, swab, urine, CSF, plasma, stool samples of suspected individuals.Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection caused by bacteria that are resistant to treatment with at least two of the most powerful first-line anti-TB medications (drugs), isoniazid and rifampin. The TB bacteria has natural defenses against some drugs, and can acquire drug resistance through genetic mutations.Resistance to anti-TB drugs can occur when these drugs are misused or mismanaged. Major spread is through air droplets originating from a person who has the disease either coughing, sneezing, speaking, or singing. psiNAT MDR TB Real Time PCR Test kit targets the specific conserved sequence encoding rpoBgene. With the PCR reaction mix provided, the amplification of template can be quantitatively monitored by the increasing fluorescence signal detected by a real-time PCR instrument. The PCR detection system includes an endogenous internal control too.

Introduction

psiNAT MTB Real Time PCR Test kit for the qualitative/quantitative detection of nucleic acidSputum, BAL, swab, urine, CSF, plasma, stool samples of suspected individuals. Mycobacterium tuberculosis (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. M.tuberculosis was found in a complex in 2019 that has at least 9 members: M. tuberculosis sensustricto, M. africanum, M. canetti, M. bovis, M. caprae, M. microti, M. pinnipedii, M. mungi, and M. orygis.Major spread is through air droplets originating from a person who has the disease either coughing, sneezing, speaking, or singing. psiNAT MTB Real Time PCR Test kit targets the specific conserved sequence encoding M. tb IS6110 gene. With the PCR reaction mix provided, the amplification of template can be quantitatively monitored by the increasing fluorescence signal detected by a real-time PCR instrument. The PCR detection system includes an endogenous internal control too.

• Pathogen: Toxoplasma gondii
• Transmission: Ingestion of oocysts from contaminated food/water or undercooked meat
• Symptoms: Flu-like symptoms, severe cases in immunocompromised individuals

• Pathogen: Chlamydia psittaci
• Transmission: Inhalation of infected bird droppings or respiratory secretions
• Symptoms: Pneumonia, fever, chills

• Pathogen: African Sleeping Sickness
• Transmission: Tsetse fly bites
• Symptoms: Fever, headaches, sleep disturbances, neurological symptoms

• Pathogen: Monkeypox
• Transmission: Animal bites, person-to-person contact
• Symptoms: Fever, rash, swollen lymph nodes

• Pathogen: Naegleria fowleri
• Transmission: Freshwater exposure (swimming, neti pots)
• Symptoms: Severe headache, fever, stiff neck, confusion

• Pathogen: Babesia microti
• Transmission: Tick bites (Ixodes scapularis)
• Symptoms: Fever, chills, sweats, hemolytic anemia